Thymosin Beta-4 (TB-4) is a naturally occurring protein composed of 43 amino acids, found in almost all human and animal cells. It plays a critical role in cellular repair, regeneration, and immune modulation. TB-4 is particularly abundant in platelets and is released at sites of tissue injury to promote healing and recovery.

TB-4 vs. TB-500: Understanding the Difference
TB-500 is a synthetic fragment of Thymosin Beta-4 (TB-4) designed to replicate specific regenerative and anti-inflammatory properties of TB-4, but it does not encompass the full range of biological activity found in the complete protein. TB-4 is superior, and plays a critical role in tissue repair, cell migration, and immune modulation, making it a powerful option for those seeking comprehensive benefits. Unlike many sources that only offer TB-500, we provide TB-4, ensuring access to its full spectrum of potential applications.

Science-Backed Research

• Actin Binding:  Binds to G-actin (globular actin) to regulate actin polymerization, which is crucial for cell migration and tissue repair.
• Wound Healing:  Promotes migration and differentiation of keratinocytes and fibroblasts, essential for tissue repair and regeneration.
• Angiogenesis:  Stimulates the formation of new blood vessels by upregulating vascular endothelial growth factor (VEGF).
• Anti-inflammatory Effects:  Reduces pro-inflammatory cytokine levels, aiding in the resolution of inflammation.
• Antioxidant Activity:  Protects cells from oxidative stress and apoptosis.
• Immune Modulation:  Enhances the function of immune cells like T-cells and macrophages.